Bodar V, et al. - Among men who participated in the Physicians’ Health Study (N = 18,960; average age: 66.1 years), researchers prospectively examined the link between coffee consumption and risk of atrial fibrillation (AF). They calculated the HRs and 95% CIs for AF by using Cox proportional hazard models. Participants were followed-up for a mean duration of 9 years, during which time the occurrence of 2,098 new cases of AF was reported. HRs (95% CI) of AF were 1.0 (reference), 0.85 (0.71-1.02), 1.07 (0.88-1.30), 0.93 (0.74-1.17), 0.85 (0.74-0.98), 0.86 (0.76-0.97), and 0.96 (0.80-1.14) for coffee consumption of rarely/never, ≤ 1 cup/week, 2-4 cups/week, 5-6 cups/week, 1 cup/day, 2-3 cups/day, and ≥ 4 cups/day, respectively. The investigators adjusted for age, smoking, alcohol intake, and exercise (P for nonlinear trend = 0.01). In a secondary analysis the multivariable adjusted HR (95% CI) of AF per standard deviation (149 mg) change in caffeine intake was 0.97 (0.92-1.02). Overall, coffee consumption of 1-3 cups daily was associated with a lower risk of AF among men.