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Coffee and pancreatic cancer risk among never-smokers in the UK prospective Million Women Study

International Journal of Cancer Nov 17, 2018

Zhou CD, et al. - Researchers examined the link between coffee consumption and pancreatic cancer risk among 309,797 never-smoking (to avoid residual confounding by smoking) UK women. These subjects self-reported typical daily coffee consumption at a mean age of 59.5 years. Record linkage to national health cancer and death registries was used to perform follow-up in these subjects for a median of 13.7 years. The investigators registered 962 incident cases of pancreatic cancers during this period. Using Cox regression, they calculated adjusted relative risks of incident pancreatic cancer with 95% confidence intervals in relation to coffee consumption at baseline. In never-smokers, little or no statistically significant link between coffee consumption and pancreatic cancer risk was noted in a meta-analysis of results from this cohort and 3 smaller prospective studies.

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