Meng Y, Chu T, Lin S, et al. - Researchers investigated how different histological types associate with the prognosis in cervical cancer patients.

• A total of 39,088 patients with a diagnosis of cervical cancer were identified between 2004 and 2016 from the Surveillance, Epidemiology, and End Results program.

• Among 36,310 patients, the most common histological type was squamous cell carcinoma (SCC) (n = 27,043, 74.5%), followed by adenocarcinoma (AC, n = 7755, 21.4%) and adenosquamous carcinoma (ASC, n = 1,512, 4.1%).

• There appeared significantly poorer prognosis for patients with AC and ASC when compared with SCC patients.

• Tumor stages and therapeutic approaches influence the prognostic impact of histologic types in cervical cancer.

• Adenocarcinoma and squamous cell carcinoma differed in prognosis only in stage II and stage III disease.

• In patients with concurrent chemoradiotherapy, significantly worse survival rates were recorded for patients with adenocarcinoma.