Ikenaga N, OhtsukaT, Nakata K, et al. - In 2016, postoperative acute pancreatitis was proposed to be defined as a specific complication of pancreatic surgery. Researchers sought to establish its presence and relevance, especially after a distal pancreatectomy. On analyzing medical records of 319 patients who underwent pancreatoduodenectomy or distal pancreatectomy, they identified 63.4% of 153 of the patients undergoing pancreatoduodenectomy and 65.7% of the 166 undergoing distal pancreatectomies experienced postoperative acute pancreatitis. Postoperative acute pancreatitis after a pancreatoduodenectomy vs a distal pancreatectomy was identified to differ in terms of clinical relevance. Development of postoperative acute pancreatitis after pancreatoduodenectomy was noted to be linked with an increase in the rate of morbidity (22.7% vs 7.1%), including postoperative pancreatic fistula (18.6% vs 1.8%), leading to higher postoperative stays (21 days vs 17 days). Postoperative acute pancreatitis in association with an elevated serum C-reactive protein ≥ 18.0 mg/dL (which we defined as a clinically relevant postoperative acute pancreatitis) was observed to be more robust indicator of the occurrence of severe complications and was independently predictive of postoperative pancreatic fistula after pancreatoduodenectomy. Development of postoperative acute pancreatitis following distal pancreatectomy was noted to be linked with experiencing similar postoperative courses concerning morbidity and the duration of postoperative stay.