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Clinical outcomes and risk factors in patients with cervical metastatic spinal cord compression after posterior decompressive and spinal stabilization surgery

Therapeutics and Clinical Risk Management Jan 17, 2019

Lei M, et al. - Researchers conducted a retrospective analysis of medical records to study the clinical results of surgery for cervical spine metastasis and identify clinical risk factors affecting postoperative survival and neurological result. Participants included 19 patients undergoing decompressive surgery and spine stabilization due to metastatic spinal cord compression in the cervical spine. Visual analog scale, ranging from 0 to 10, was used to assess the worst pain, average pain, and pain interference for each patient at baseline and following surgery. Using the Japanese Orthopedic Association Score (JOAS), neurological recovery was evaluated. The type of primary cancer, ambulatory status, extra-spinal bone metastasis, 125I seed brachytherapy, and surgery-related complication status were found to be significantly linked to postoperative survival in patients with metastatic spinal cord compression in cervical spine after surgery. For neurological recovery and pain control with a tolerable rate of complications, posterior decompression and spine stabilization for painful cervical spine metastasis resulting from spinal cord compression were found to be effective. Complications related to surgery occurred in 26.3% of patients.

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