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Clinical features and psychiatric comorbidities in military veterans with schizophrenia with or without suicidality

Journal of Psychiatric Research Sep 11, 2021

Sher L, Kilmade ME, Feinberg A, et al. - Researchers recommend inclusion of identification of individuals with comorbid mood disorders/symptoms, post-traumatic stress disorder (PTSD), alcohol use disorder, marked positive symptoms, and schizotypal features in suicide risk assessment in veterans with schizophrenia.

  • Two groups of veterans with schizophrenia [suicide ideators and/or attempters (SIA) and individuals without a history of suicidal ideation or attempts (no-SIA)] were assessed.

  • In bivariate analyses, SIA vs no-SIA patients had higher Positive and Negative Syndrome Scale for Schizophrenia (PANSS)-Positive Symptom scores, PANSS-General Psychopathology scores, Hamilton Depression Rating Scale (HDRS) total score, HDRS-Paranoid symptoms item score, and Schizotypal Personality Questionnaire (SPQ) total scores.

  • Mood disorders, PTSD, and/or alcohol use disorder were more frequently reported among SIA patients.

  • The difference between the groups was indicated to be driven by the HDRS total score and presence/absence of comorbid mood disorder.

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