Clinical EEG slowing correlates with delirium severity and predicts poor clinical outcomes
Neurology® Oct 04, 2019
Kimchi EY, Neelagiri A, Whitt W, et al. - In this prospective study involving 200 patients (median age 60 years), researchers determined which findings on routine clinical EEGs correlate with delirium severity across various presentations and determined whether EEG findings independently anticipate important clinical results. Data reported that 121 patients (60.5%) met delirium criteria. Longer hospitalizations, worse functional outcomes, and increased mortality were correlated with EEG slowing, even after adjustment for delirium presence or severity. Even with normal arousal, slowing was common in delirium. Findings suggested that generalized slowing on routine clinical EEG is strongly correlated with delirium and can be a valuable biomarker for the severity of delirium. Furthermore, generalized EEG slowing should trigger increased concern about the prognosis of patients with altered mental status.
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