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Clinical course, associated factors, and blood pressure profile of delayed-onset postpartum preeclampsia

Obstetrics and Gynecology Nov 05, 2019

Redman EK, et al. - Researchers sought for clinical risk factors associated with the development of delayed-onset postpartum preeclampsia. In addition, they sought to characterize management and subsequent risk of cardiovascular disease. In this case–control study, they performed a comparison of women admitted to the hospital with delayed-onset postpartum preeclampsia (n = 121)(defined as a new diagnosis of preeclampsia presenting between 48 hours and 6 weeks postpartum) vs women with full-term, uncomplicated pregnancies without a hypertensive diagnosis or diabetes (n = 26,936). Relative to women in the control group, women with delayed-onset postpartum preeclampsia were significantly more frequently of non-Hispanic black race (31.4% vs 18.0%), obese (39.7% vs 20.1%), and deliver by cesarean (40.5% vs 25.8%). Variable management strategies were undertaken in relation to delayed-onset postpartum preeclampsia. The clinical risk factors for delayed-onset postpartum preeclampsia substantially overlapped on those for antepartum preeclampsia. In addition, the findings suggest an association of delayed-onset postpartum preeclampsia with an increased risk of progression to chronic hypertension.
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