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Clinical characteristics and outcomes of patients with coronavirus disease 2019 (COVID-19) and rheumatic disease: A comparative cohort study from a US ‘hot spot’

Annals of Rheumatic Diseases May 29, 2020

D’Silva KM, Serling-Boyd N, Wallwork R, et al. - This study was attempted to assess changes in manifestations and outcomes of coronavirus disease 2019 (COVID-19) infection between those with and without rheumatic disease. Researchers performed a comparative cohort study of patients with rheumatic disease and COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR) to compare in a 1:2 ratio with matched comparators on age, gender and date of COVID-19 diagnosis, between 1 March and 8 April 2020, at Partners HealthCare System in the greater Boston, Massachusetts area. Researchers analyzed differences in demographics, clinical features and outcomes of COVID-19 infection. Fifty-two rheumatic disease patients were distinguished with COVID-19 (mean age, 63 years; 69% female) and matched these to 104 non-rheumatic disease comparators. There was a need of mechanical ventilation for the patients with rheumatic disease and COVID-19 infection but had similar clinical features and hospitalisation rates as those without rheumatic disease. These data have important implications for patients with rheumatic disease but need future confirmation.

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