Minamizato T, et al. – A pilot study was undertaken to investigate the efficacy and safety of autogenous partially demineralized dentin matrix (APDDM) prepared onsite, for clinical application in bone regeneration procedures related to implant dentistry, including socket preservation, alveolar ridge augmentation, and maxillary sinus floor augmentation. Results of this study suggested that APDDM is an efficient, safe, and reasonable bone substitute and this material has the potential to become one of the options as a bone substitute in implant dentistry.