Sasaki G, Watanabe Y, Yasui Y, et al. - The present study was performed to clarify the efficacy of the induced membrane technique (IMT) using beta-tricalcium phosphate (β-TCP) for the reconstruction of segmental bone defects by evaluating clinical and radiological outcomes, and the effect of defect size and operated site on surgical outcomes. Between 2014 and 2018, researchers performed a review of the medical records of consecutive 35 lower limbs (30 males and five females; median age 46 years (interquartile range 40 to 61)) treated with IMT using β-TCP. Individuals were classified into ≥ 50 mm and < 50 mm defect groups and into femoral reconstruction, tibial reconstruction, and ankle arthrodesis groups. The data exhibited that using β-TCP, IMT provided satisfactory clinical and radiological outcomes for segmental bone defects in the lower limbs; surgical outcomes were not influenced by bone defect size or operated part.