Galofre M, et al. - Oral probiotics appear to improve the treatment of periodontal diseases but there is limited evidence on their efficacy in the treatment of peri-implant diseases. This topic was addressed in this study, wherein, it was found that the administration of a daily lozenge of Lactobacillus reuteri, an oral probiotic, for 30 days, together with mechanical debridement of the whole mouth, improved the clinical parameters of implants with mucositis or peri-implantitis over a period of at least 90 days in patients having a history of periodontal disease, however, the microbiological effect was much more limited. Overall, findings indicate that probiotics afford an alternative therapeutic approach to consider in the prevention and treatment of peri-implant diseases.