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Clinical and biological factors associated with recurrences of severe toxoplasmic retinochoroiditis confirmed by aqueous humor analysis

American Journal of Ophthalmology Feb 26, 2019

Matet A, et al. - Investigators examined the clinical and biological factors affecting recurrence of severe toxoplasmic retinochoroiditis (TRC) as affirmed by aqueous humor analysis among 44 cases in this retrospective case series. They noted a higher risk of recurrence rapidly after an episode. A decrease in the recurrence risk with a higher number of intense bands on aqueous T. gondii immunoblot, and incline in risk when venous vasculitis was present originally, in univariate analysis. They found a near-significant risk elevation after pyrimethamine/azithromycin therapy. They did not find any impact of intravenous corticosteroid administration, oral corticosteroid administration, aqueous Goldmann-Witmer coefficient (GWC), and T. gondii polymerase chain reaction (PCR) on recurrences.
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