Rattanawong P, et al. - Researchers assessed the link between chronic kidney disease (CKD) and mortality and procedural complications in transcatheter aortic valve replacement (TAVR) by analyzing published TAVR studies that compared the risk of mortality and procedural complications in CKD patients vs control patients. These studies were identified from the databases of MEDLINE and EMBASE from inception to May 2018. Overall, 12 studies, including 42,703 CKD patients and 51,347 controls, were analyzed. A significantly higher risk of 30-day overall mortality, long-term cardiovascular mortality, and long-term overall mortality, as well as procedural complications including pacemaker requirement and bleeding, was observed in CKD patients vs controls. in patients with CKD who underwent TAVR vs controls, a significant increased risk of mortality and procedural complications was seen.