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Chronic hemodialysis is associated with lower trabecular bone score, independent of bone mineral density: A case-control study

Archives of Osteoporosis Nov 17, 2018

Dusceac R, et al. - Authors evaluated the lumbar spine (LS) trabecular bone score (TBS) in hemodialysis (HD) patients compared with subjects with normal kidney function matched for age, sex, and LS bone mineral density (BMD). They simultaneously controlled for sex, age, and LS BMD. Findings suggested lower TBS in HD patients than controls matched for LS BMD, indicating altered bone microarchitecture. Moreover, at any LS BMD the magnitude of TBS reduction in HD patients is constant. The absolute 10-year fracture risk is partially corrected by the adjustment for TBS. Compared to the matched controls, HD patients had significantly lower LS TBS, TBS T-score and TBS Z-score.
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