Dal-Fabbro R, et al. - The effect of chronic alcohol consumption on apical periodontitis was investigated in rats. Researchers arranged 32 male Wistar rats into 4 groups: Control (C): without apical periodontitis and non-alcoholic diet; (AL): without apical periodontitis and alcoholic diet; (AP): with apical periodontitis and non-alcoholic diet; (AP+AL): with apical periodontitis and alcoholic diet. Findings revealed a significant effect of an alcoholic diet on the severity of apical periodontitis, indicating an exacerbation of the inflammatory response and osteoclastogenesis in correlation with the alcoholic diet.