Dias-Santos A, Tavares Ferreira J, Pinheiro S, et al. - Using linear regression models, researchers compared choroidal thickness (CT) between SLE patients without ophthalmologic manifestations and a control group in whom systemic autoimmune diseases were excluded, as well as studying the effects in CT of disease duration, activity index, medication and systemic comorbidities. To measure CT in 13 locations, subfoveally and at 500-μm intervals along a horizontal and a vertical section from the fovea, cross-sectional study where spectral-domain optical coherence tomography with enhanced depth imaging was used. Participants in the study were 68 SLE patients and 50 healthy controls. According to findings, CT in SLE seems to be thinner, especially in the subset of patients with nephritis and taking anticoagulants, indicating more advanced systemic vascular disease. It may also be possible to alter choroidal responses to hemodynamic changes in SLE.