Andrianello S, Bannone E, Marchegiani G, et al. - Researchers sought to report the characteristics of postoperative acute pancreatitis occurring after distal pancreatectomy. Among 368 patients who underwent distal pancreatectomies, 67.9% and 28.8% experienced postoperative acute pancreatitis and postoperative pancreatic fistula, respectively. Observations thereby suggest frequent occurrence of postoperative acute pancreatitis after distal pancreatectomy. An increased rate of severe morbidity was observed among patients who developed postoperative acute pancreatitis. Following were identified to be independent predictors of postoperative acute pancreatitis: neoadjuvant therapy, age ≥ 65 y, duct size, pancreatic thickness, resection at the body-tail level, and neuroendocrine histology were. In addition, postoperative acute pancreatitis was identified to be an independent predictor of postoperative pancreatic fistula. Among patients who developed postoperative acute pancreatitis, 37% developed postoperative pancreatic fistula. A statistically significantly raised rate of biochemical leakage and bacterial contamination in the peripancreatic drainage fluid were noted among patients developing postoperative acute pancreatitis alone.