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Characteristics of melanoma in white and nonwhite children, adolescents, and young adults: Analysis of a pediatric melanoma institutional registry, 1995-2018

Pediatric Dermatology Apr 21, 2019

Afanasiev OK, et al. - Nonwhite/multiethnic vs white children, adolescents, and young adults with melanoma or atypical melanocytic neoplasms, including atypical Spitz tumors were examined for the clinical differences. Analyzing a cohort of 55 patients (< 25 years of age) prospectively followed from 1995 to 2018 in the Stanford Pigmented Lesion and Melanoma Program, they classified 17 patients (9 males and 8 females) as nonwhite (predominantly skin phototype IV) and of Hispanic, Asian, or Black/African American ethnicity, and 38 patients (21 males and 17 females) as white (predominantly phototypes I/II). In this cohort, 87% of whites were diagnosed with melanomas, compared to 65% of nonwhites, with the remainder representing mainly atypical Spitz tumors. The patient or family usually brought the attention of a health care provider to lesions. Nonwhites more frequently presented at a younger mean age (10.9 years vs 15.4 years) and with pink/clinically amelanotic tumors (59% vs 24%) compared with whites.
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