Zhou XZ, Shi R, Wang J, et al. - In the present study, the researchers sought to assess the characteristics of coronary artery disease (CAD) in patients with subclinical hypothyroidism (SCH) utilizing coronary computed tomographic angiography (CCTA). Two hundred thirty-four consecutive SCH patients with coronary plaques identified on CCTA were involved retrospectively from April 1, 2018, to June 30, 2020, and were further subdivided into the different degree of SCH groups (mild SCH vs moderate SCH vs severe SCH: 143 vs 62 vs 28) and different gender groups (men with SCH vs women with SCH:116 vs 118). Severe SCH patients had fewer calcified plaques and more non-calcified plaques than mild SCH patients. Men with SCH have a higher total plaque burden than women, and severe SCH is related to noncalcified plaques. The authors believe that it is critical to screen for coronary plaque in SCH patients, particularly those with severe SCH and men with SCH.