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Characteristics and outcomes of patients with ophthalmologic involvement in giant-cell arteritis: a case-control study

Seminars in Arthritis and Rheumatism Mar 22, 2020

Dumont A, Lecannuet A, Boutemy J, et al. - The present study was intended to report the characteristics and outcome of individuals with giant-cell arteritis (GCA)-related ophthalmologic involvement at diagnosis. Researchers retrieved 104 individuals with visual symptoms at GCA diagnosis and correlated them to 104 age- and gender-matched controls without ophthalmologic involvement in a retrospective single-center cohort of 409 consecutive patients with GCA. It was indicated that individuals with visual symptoms displayed less fever, less polymyalgia rheumatica and lower acute phase reactants in comparison compared with controls. The study found ophthalmologic involvement in one-quarter of our GCA individuals. IT was noted that anterior ischemic optic neuropathy is still correlated with the worst visual prognosis, and IV methylprednisolone pulses did not decrease the risk of blindness in the study.

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