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Changing rates of chronic Pseudomonas aeruginosa infections in cystic fibrosis: A population-based cohort study

Clinical Infectious Diseases Sep 19, 2018

Crull MR, et al. - Considering the association of chronic Pseudomonas aeruginosa lung infection with significant morbidity and mortality in cystic fibrosis (CF) patients, researchers investigated if recent advances in care have affected the rates of developing new chronic P. aeruginosa infection among adolescents and adults with CF. The cohort consisted of 15,504 individuals with CF followed in the Cystic Fibrosis Foundation Patient Registry aged ≥13 years without chronic P. aeruginosa at baseline. Findings revealed a significant decrease in the risk of developing chronic P. aeruginosa infection between 2003 and 2012. A decrease from 14.3% in 2003 to 6.4% in 2012 was noted in the annual rates of developing the new infection.

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