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Changes in peripapillary and macular vascular density after laser selective trabeculoplasty: An optical coherence tomography angiography study

Acta Ophthalmologica Mar 10, 2021

Gillmann K, et al. - In this prospective observational study, researchers determined the impact of laser trabeculoplasty on peripapillary retinal nerve fibre layer thickness (RNFL), fovea avascular zone, peripapillary and macular vessel density (VD) in glaucoma using optical coherence tomography angiography. This investigation was carried out at the Glaucoma Research Centre, Montchoisi Clinic, Lausanne, Switzerland. Thirty‐seven eyes with primary open‐angle glaucoma from 21 patients were involved. After laser trabeculoplasty, peripapillary and macular VD increased temporarily by 6 months before returning to near-baseline values. There was no correlation between microvascular fluctuations and IOP, and no significant effect of laser trabeculoplasty on VD or RNFL was noted at 6 months despite persistent IOP reduction. More research is needed to determine the exact causes and clinical implications.

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