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Changes in ganglion cell-inner plexiform layer thickness and retinal microvasculature in hypertension: An optical coherence tomography angiography study

American Journal of Ophthalmology Feb 26, 2019

Lim HB, et al. - Authors examined 201 eyes from 117 healthy cases and 84 hypertensive subjects without any ocular anomalies to estimate the retinal blood flow in hypertensive candidates using optical coherence tomography angiography (OCTA) and also the correlation between blood flow metrics and ganglion cell-inner plexiform layer (GC-IPL) thickness. They found that the average GC-IPL and peripapillary retinal nerve fiber layer (RNFL) thicknesses in Hypertension Group 2 (disease period ≥5 years) were significantly thinner as compared to the control group. A decrease in the 3 mm total area of the vessel density (VD) and perfusion density (PD) was noted in comparison to the control group and Hypertension Group 1 (disease periods <5 years).
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