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Changes in conventional cardiovascular risk factors and the estimated 10-year risk of acute myocardial infarction or cerebral stroke in Sami and non-Sami populations in two population-based cross-sectional surveys: The SAMINOR Study

BMJ Open Jul 25, 2019

Siri SRA, et al. – Via assessing results from two cross-sectional surveys of individuals aged 40–79 years who participated in SAMINOR 1 (n=6,417) and/or SAMINOR 2 (n=5,956), researchers explained alterations in cardiovascular risk factors and in the estimated 10-year risk of acute myocardial infarction (AMI) or cerebral stroke (CS) between SAMINOR 1 (2003–2004) and SAMINOR 2 (2012–2014), and investigated whether these alterations varied between Sami and non-Sami. Sami men demonstrated smaller reductions in mean HDL cholesterol and elevations in mean triglyceride levels; non-Sami men exhibited no alteration in these variables. Non-Sami women displayed elevations in mean HDL cholesterol whereas Sami women had no variation. No alterations in triglyceride levels in non-Sami and Sami women were noted. Systolic and diastolic blood pressure levels declined by 3.6 mm and 1.0 mm and 3.1 Hg and 0.7 Hg in women and in men, respectively. In women and men, mean waist circumference grew by 6.7 and 5.9 cm, respectively. The odds of being a smoker declined by 35% and 46% in women and men, respectively. The calculated 10-year risk of AMI or CS diminished in all strata of sex and ethnicity; however, Sami women had a smaller drop vs non-Sami. Therefore, a drop in mean cholesterol, blood pressure, smoking, hypertension (women only) and a 10-year risk of AMI or CS was noted regardless of ethnicity, but there was an increase in waist circumference. Moreover, in cardiovascular risk factors, relatively minor ethnic variations were discovered in changes.

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