Araghi M, et al. - In seven high-income countries [Australia, Canada, Denmark, Norway, New Zealand, Ireland, and the United Kingdom], researchers investigated longitudinal and generational changes in the incidence of colon and rectal cancer. However, significant increases in the incidence of colon cancer in people younger than 50 years in Denmark (by 3·1%), New Zealand (2·9%), Australia (2·9%) and the UK (1·8%) were noted in the most recent 10-year period for which data were available. In this age group in Canada (by 3·4%), Australia (2·6%), and the UK (1·4%), significant increases in the incidence of rectal cancer were also noted. In some of the countries in this study, a significant increase in the incidence of colorectal cancer in people younger than 50 years was noted. They noted non-linear cohort effects for rectal rather than colon cancer in all countries.