Sundbøll J, et al. - Researchers investigated the association of being overweight and changes in weight status during childhood with the risk of venous thromboembolism (VTE) in adulthood by using Danish medical registries in this population-based cohort study involving Danish schoolchildren aged 7-13 years. Of 313,998 children, 5,007 girls ad 5,397 boys received a diagnosis of VTE as adults. A 1.30- to 1.50-fold increased risk of VTE in adulthood was reported in children with a body-mass index (BMI) persistently above the 75th percentile vs children with a normal BMI (25th to 75th percentile category) at both ages. A 1.35- to 1.70-fold increased risk of adulthood VTE was observed among children with a BMI increase from the 25th to 75th or > 75th to 90th percentile to a higher percentile category. Overall, children having a persistently above-average BMI demonstrated a higher adulthood VTE risk. An additional increase in the VTE risk was noted in relation to weight gain from 7 to 13 years of age; the risk was completely regressed by remission from overweight by 13 years of age.