Changes in attentional function in patients from before through 12 months after breast cancer surgery
Journal of Pain and Symptom Management Feb 14, 2020
Kohler C, Chang M, Allemann-Su YY, et al. - As nearly 75% of patients with breast cancer record changes in attentional function, researchers sought to determine interindividual variability in the trajectories of self-reported attentional function and investigated the demographic, clinical, symptom, and psychosocial adjustment characteristics that are linked with initial levels and with changes in attentional function from before through 12 months after breast cancer surgery. The enrollment of 396 women was done before surgery. These women were made to complete the Attentional Function Index (AFI) before and nine times within the first 12 months after surgery. The estimated preoperative AFI score was 6.53; the estimated linear rate of change in AFI score was an increase of 0.054 for each additional month. Lower levels of attentional function before surgery was observed in correlation to the following factors: higher levels of comorbidity, receipt of adjuvant chemotherapy, higher levels of trait anxiety, fatigue, and sleep disturbance, and lower levels of energy and less sense of control. Fewer improvements in attentional function were observed over time among patients who were nonwhite, did not have a lymph node biopsy, had received hormonal therapy, and had less difficulty coping with their disease. These findings may aid in recognizing patients with breast cancer at greater risk for impaired self-reported cognitive function and in guiding the prescription of more personalized interventions.
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