Change in hazard rates of recurrence over time following diagnosis of endometrial cancer: An age stratified multicentre study from the FRANCOGYN group
European Journal of Surgical Oncology Aug 03, 2018
Ouldamer L, et al. - Via analyzing data of 1153 women who received primary surgical treatment for stage I-III endometrial cancer (EC) between January 2001 and December 2013 from a prospectively maintained multicentre database, researchers determined the patterns of recurrence and investigated the high-risk periods for recurrence in function of age. During follow-up, a significant recurrence rate remained maintained among women with EC aged ≥ 65 years irrespective of the stratification (locoregional recurrence, distant recurrence, ESMO/ESGO/ESTRO subgroup). Obsevations suggest no uniform distribution of annual hazard ratio (HR) of recurrence over time. However, the recurrence seems dynamic and markedly determined by prognostic factors at diagnosis (advanced age, advanced disease ESMO/ESGO/ESTRO subgroup).
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