Bansal N, Zelnick LR, Soliman E, et al. - Researchers undertook this observational, case-cohort analysis to examine the links of longitudinal alterations in N-terminal pro-B-type natriuretic peptide (NT-proBNP), high sensitivity troponin T (hsTnT), galectin-3, growth differentiation factor-15 (GDF-15), and soluble ST-2 (sST-2) with incident heart failure (HF) and atrial fibrillation (AF) in patients suffering from chronic kidney disease (CKD). The incident HF study comprised 789 (which included 138 incident HF cases) and the incident AF study involved 774 participants (which included 123 incident AF cases). Findings showed that rises in NT-proBNP in CKD were significantly related to greater risk of incident HF and AF; and rises in sST2 were found to be related to HF. Experts found that changes in hsTnT, galectin-3 or GDF-15 were not associated with incident HF or AF.