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Chance of live birth: A nationwide, registry-based cohort study

Human Reproduction Jan 11, 2021

Kolte AM, Westergaard D, Lidegaard O, et al. - Researchers here examined if and how the sequence of prior pregnancy events (pregnancy losses, live births, ectopic pregnancies, molar pregnancy and stillbirth), obstetric complications and maternal age influence chance of live birth in the next pregnancy. In addition, they determined the predictive value of prior events for the outcome. They performed a nationwide, registry-based cohort study of 1,285,230 women with a total of 2,722,441 pregnancies from 1977 to 2017. Findings revealed a negative effect of obstetric complications, still birth, ectopic pregnancies and pregnancy losses on the chance of live birth in the next pregnancy. A larger impact was evident in correlation with consecutive, identical pregnancy outcomes (pregnancy losses, live births or ectopic pregnancies) immediately preceding the next pregnancy vs the total number of any outcome. However, there appeared an insufficient value of pregnancy history and age for predicting the outcome of an individual woman’s next pregnancy.

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