Kamenaga T, Takayama K, Ishida K, et al. - This study was intended to ascertain if femoral component position relative to tibial insert could affect clinical outcomes after fixed-bearing unicompartmental knee arthroplasty (UKA). Researchers evaluated the femoral component position relative to the tibial insert of 66 patients with anteromedial osteoarthritis and osteonecrosis of the knee who had undergone fixed-bearing UKA at 2 weeks postoperatively. Individuals were categorized according to the contact point of the femoral component with the tibial component: group M (medial), 18 knees; group C (central), 30 knees; and group L (lateral), 18 knees. They further evaluated patient-derived clinical scores applying the 2011 Knee Society Score preoperatively and at 2 years postoperatively and compared among the three groups using analysis of variance. This study's findings reveal that central implantation of the femoral component relative to the tibial insert plays an important role in decreasing pain and could outcome in better patient satisfaction after fixed-bearing UKA at 2 years postoperatively. The results consider that after fixed-bearing UKA, surgeons should set the femoral component at the center to the tibial insert for better patient satisfaction and higher active knee flexion.