Vargas-Santos AB, et al. - All residents of Skåne (Sweden, n = 832,258 persons) age ≥18 years in the year 2002 were included in this study to investigate cause-specific mortality beyond cardiovascular diseases (CVDs) in patients with gout in comparison with the general population. A total of 19,497 had a new diagnosis of gout and they were matched with 194,947 comparators. A greater prevalence of chronic kidney disease, metabolic disease, and CVD was noted in individuals with gout. Gout was correlated with 17% heightened hazard of all-cause mortality overall, ie, 23% in women and 15% in men. The most robust relationships in terms of cause-specific mortality, were observed in the association of gout to the risk of death because of renal disease, diseases of the digestive system, infections, and dementia. Therefore, various non-CV causes of mortality are increased in persons with gout, emphasizing the need for improved management of comorbidities.