Desalew A, Sintayehu Y, Teferi N, et al. - Researchers performed a facility-based prospective follow-up study to determine the causes and predictors of neonatal mortality among infants admitted to neonatal intensive care units in eastern Ethiopia. This investigation was carried out among neonates admitted to neonatal intensive care units of public hospitals of eastern Ethiopia from November 1 to December 30, 2018. Data were obtained utilizing a pretested structured questionnaire and a follow-up checklist. Data reported that the proportion of facility-based neonatal mortality was 20%. Complications of preterm birth, birth asphyxia, neonatal infection, meconium aspiration syndrome, respiratory distress syndrome, and congenital malformation were the causes of death. Among infants admitted to the neonatal intensive care units of public hospitals in eastern Ethiopia, low birth weight, preterm births, length of stay of the neonatal intensive care unit, low 5 min APGAR score, hyperthermia, and initiation of feeding were predictors of neonatal death. An unacceptably high proportion of facility-based neonatal deaths. Preventable and treatable were the main causes of death. Improving the timing and quality of antenatal care is therefore essential for early detection, anticipation of high-risk newborns and timely interventions. In addition, early initiation of feeding and improved linkage to tertiary health facilities could lead to a reduction in neonatal death in this setting.