Silverberg JI, et al. - Authors coveted an evaluation of the tie-up between juvenile dermatomyositis (JDM) with the cardiovascular and cerebrovascular risk factors in US children. Inpatients with JDM demonstrated substantially higher odds of cardiovascular and cerebrovascular comorbidities. It was discovered that adolescents, girls and racial/ethnic minorities were at the highest risk.

Methods

• Data analysis was carried out from the 2002-12 National Inpatient Sample.
• The study cohort comprised of ∼20% of all US hospitalizations (n = 14,535,620 paediatric hospitalizations).

Results

• A prominent link was displayed between JDM with 12 of 13 comorbidities.
• These factors included hypertension [survey logistic regression; crude odds ratio (95% CI): 22.25 (15.51, 31.92)], obesity [5.87 (3.44, 10.02)], uncomplicated diabetes [7.95 (4.21, 15.00)], lipid abnormalities [5.84 (2.77, 12.31)], especially lipodystrophy [151.08 (38.24, 596.86)], peripheral and visceral atherosclerosis [10.09 (3.70, 27.56)], late effects of cerebrovascular disease [15.49 (2.37, 101.43)], personal history of transient ischaemic attack and cerebral infarction [10.82 (2.46, 47.65)], pulmonary circulatory disorder [12.23 (2.59, 57.73)], arrhythmia [3.93 (2.80, 5.52)], bradycardia [4.22 (2.65, 6.74)] and hypotension [2.62 (1.27, 5.39)].