Marshall CH, Al-Mallah MH, Dardari Z, et al. - In this retrospective cohort study, researchers examined 49,143 consecutive patients who underwent clinician-referred exercise stress testing from 1991 through 2009 in order to determine the link between cardiorespiratory fitness (CRF) and lung and colorectal cancer outcomes. The study sample included participants aged 40 to 70 years who were cancer-free and received treatment within the Henry Ford Health System in Detroit, MI. The different categories of CRF, measured in metabolic equivalents of task, were < 6 (reference), 6-9, 10-11, and ≥ 12. Participants were followed-up for a median duration of 7.7 years. Overall, a lower risk of incident lung and colorectal cancers in men and women, as well as a lower risk of all-cause death among those with lung or colorectal cancer, was reported in relation to a higher CRF.