Bansal N, Zelnick L, Go A, et al. - Among adults with chronic kidney disease registered in a prospective, multicenter study, researchers examined incident heart failure (HF) in correlation with NT-proBNP (N-terminal pro-B-type natriuretic peptide), high-sensitivity troponin T (hsTnT), galectin-3, growth differentiation factor-15 (GDF-15), and soluble ST2 (sST2). They measured all biomarkers at baseline. Incident HF as a primary outcome and HF with preserved ejection fraction (EF ≥ 50%) and reduced ejection fraction (EF < 50%) as secondary outcomes were evaluated. Findings revealed an association between rises of NT-proBNP, hsTnT, GDF-15, sST2 and incident HF in patients with chronic kidney disease. A borderline link of galectin-3 with incident HF was also observed. More strong link of NT-proBNP and hsTnT with HF with reduced EF was evident, while the links of the newer biomarkers GDF-15 and sST2 were stronger for HF with preserved EF.