DeSantis CE, Miller KD, Dale W, et al. - Researchers determined the cancer burden among adults aged 85 years and older in the United States via integrating data from the National Cancer Institute, the North American Association of Central Cancer Registries, and the National Center for Health Statistics. According to their findings, there will be about 140,690 cancer cases diagnosed and 103,250 cancer deaths among the oldest old in the United States in 2019. Lung, breast, prostate, and colorectum cancers are the most common cancer types in the oldest old—the same as in the general population. They found that since 1990, which saw the highest cancer incidence rates among the older US men and women, cancer incidence rates have declined, with the pace accelerating during the last decade. For some cancers (eg, lung cancer and melanoma), variations in trends were observed in the oldest age group vs adults aged 65 to 84 years, suggesting high risks in the oldest generations. The lowest relative survival of any age group was observed in patients with cancer who were aged 85 years and older. The chance of these people receiving surgical treatment for their cancers was also lower. Not only the complexities of treating older patients, including the presence of multiple comorbidities, functional declines, and cognitive impairment, but also competing mortality risks and undertreatment may be indicated by this difference.