Kim KJ, et al. - In this analysis involving 100,867 participants in the 2012 Korean Community Health Survey, researchers assessed the link between cancer risk and long-term exposure to ambient particulate matter <10 μm (PM₁₀) and ozone (O₃), according to obesity and health-related behaviors. Multiple logistic regression was used to assess cancer risks for interquartile increases in PM₁₀ and O₃, stratified by age, sex, obesity, and health-related behaviors. Findings revealed an increased cancer risk in association with long-term exposure to PM₁₀ and O₃. Based on obesity status, age, sex, and health-related behaviors, variations in this risk were evident. After adjusting for confounding factors, obese participants aged ≥ 50 years were found to have increased cancer risk. Non-obese participants did not exhibit similar trends. An increased cancer risk was observed in men, ever smokers, and inactive participants among obese individuals aged ≥ 50 years who had been exposed to PM₁₀. In relation to O₃, a markedly higher cancer risk was observed among obese adults > 50 years, irrespective of sex or health-related behaviors.