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Cancer-attributable mortality among solid organ transplant recipients in the United States: 1987 through 2014

Cancer May 06, 2019

Noone AM, et al. - Among solid organ transplant recipients in the US (1987-2014), researchers investigated incident cancers and deaths by using linked transplantation and cancer registry data. They used Cox models to determine population-attributable fractions of deaths due to cancer and corresponding cancer-attributable mortality rates. Cancer development was reported in 15,012 of 221,962 solid organ transplant recipients. Findings revealed that nearly 13% of deaths among solid organ transplant recipients was caused by cancer. Lung cancer was the most common among recipients aged ≥50 years and non-Hodgkin lymphoma was the most common among children. With age and length of time since transplantation, cancer-attributable mortality increased, and thus, an increasing burden of cancer deaths will be seen as recipients live longer.

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