Zhu X, Sun X, Zeng Y, et al. - A systematic review and meta-analysis were to ascertain whether this scheme could reduce SSIs and periprosthetic joint infections (PJIs) following elective primary total joint arthroplasty (TJA). Researchers conducted a systematic search in MEDLINE, Embase, and the Cochrane Library until October, 2019. They included nine studies in our meta-analysis. They further conducted additional analyses to assess whether there were differences in postoperative SSIs caused by S. aureus or other bacteria. The pooled data illustrated that nasal S. aureus screening and decolonization dramatically mitigated the risk of SSI, PJI, and superficial infection compared to nondecolonization group. The study's found that S. aureus screening and decolonization before elective primary THA and TKA could significantly reduce the risk of SSI and PJI. Nevertheless, more research is required to further assess the effect of S. aureus screening and decolonization on infection risk after TJA.