Staiger RD, Gerns E, Castrejón Subirà M, et al. - Researchers examined whether overall severe morbidity after major surgery can be predicted with determining specific patterns of early postoperative complications, warranting early escalation of care and prevention of failure to rescue. In a single tertiary center, they analyzed all 90-day postoperative events over a 3-year period following complex pancreas, liver, and rectal surgeries, and liver transplantation. Findings suggest occurrence of multiple complications of any cause or severity within the first postoperative days to represent a “warning-signal” for overall high morbidity by 90 days. They emphasize using this warning-signal to trigger an escalation of care to limit failure to rescue and eventually poor outcome.