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C-reactive protein and stroke risk in blacks and whites: The REasons for Geographic and Racial Differences in Stroke Cohort

American Heart Journal Aug 21, 2019

Evans CR, Long DL, Howard G, et al. - In view of the observation that relative to whites, blacks have higher stroke incidence and also higher C-reactive protein (CRP), researchers sought to study how CRP is associated with ischemic stroke risk in blacks and whites. In REGARDS, an observational cohort study, they recruited and followed 30,239 black and white Americans aged 45 and older for ischemic stroke. Observations revealed an elevated risk among whites in correlation with CRP in the range from 3 to 10 mg/L and even higher for CRP > 10 mg/L, however, blacks display such an association only for CRP > 10 mg/L. This suggests that among blacks and whites, CRP was not equally useful in stroke risk assessment.
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