de Sousa DA, et al. - In this investigation, researchers characterized the brush sign (BS), an abnormally accentuated signal drop in paramagnetic-sensitive magnetic resonance sequences of the subependymal and deep medullary veins previously reported in an acute ischemic stroke, in patients with thrombosis of the cerebral veins and sinuses and examined its link with clinical severity, thrombosis extent, parenchymal brain lesion, and clinical prognosis. BS was seen in gradient-echo T2*weighted (T2*WI) in 16% and susceptibility-weighted imaging in 13% of cases in 118 included patients. In almost one in 7 patients with acute thrombosis of the cerebral veins and sinuses, BS in T2*WI and susceptibility-weighted imaging was seen. BS has been linked significantly with ipsilateral parenchymal brain lesion, extent of thrombosis, and manifestation with focal neurological deficits. This suggests that BS may be a severity marker in cerebral veins and sinuses thrombosis.