Hoogman M, et al. - Cortical features associated with attention deficit hyperactivity disorder (ADHD) were investigated in case subjects with ADHD (N=2,246) and control subjects (N=1,934) for children, adolescents, and adults separately. In ENIGMA-ADHD, a consortium of 36 centers, comparison of cortical thickness and surface area (based on the Desikan–Killiany atlas) was done. Children with ADHD showed lower surface area values, mainly in frontal, cingulate, and temporal regions; the greatest significant effect was for total surface area (Cohen’s d=−0.21). Children with ADHD also showed lower fusiform gyrus and temporal pole cortical thickness. Adolescent or adult groups displayed neither surface area nor thickness differences. The surface area in several regions had familial effects. Correlation of surface area (but not thickness) with attention problems in the Generation-R sample was observed min an overlapping set of regions.