Gosset A, Escanes C, Pouilles JM, et al. - Researchers conducted this case-control study for analyzing the bone mineral density (BMD) in women with and without pelvic deep infiltrating endometriosis (DIE) who underwent early bilateral oophorectomy (BO). The sample consisted of 83 women who underwent early BO before the age of 45 years, 31 for DIE and 52 for another clinical condition. All of the women were medically tested and completed a standardized computer-assisted questionnaire to document their clinical and historical details. In women who underwent early BO, higher lumbar spine and femoral neck BMDs are linked to a higher risk of pelvic DIE. This may be expected to the extent that endometriosis is itself associated with enhanced estrogen status, although further studies are required to confirm this hypothesis. Such findings indicate that BMD measurement might contribute to the hormonal management of surgical menopause in women with DIE.