Ho MH, Huang D, Ho CW, et al. - Among patients with heart failure with reduced ejection fraction (HFrEF) hospitalised for acutely decompensated heart failure (ADHF), this prospective observational study was conducted to examine the link between haemodynamic parameters, body water content and worsening of kidney function. Participants were 51 HFrEF patients (age: 73 ± 14 years, male: 60%, left ventricular ejection fraction: 33.3% ± 9.9%) hospitalised for ADHF. Experts serially collected echocardiographic-determined haemodynamic parameters and body volume ascertained employing a bioelectric impedance analyser. Intravenous furosemide 160 mg/day was delivered in all patients for 3 days. In participants, worsening of renal function was evident in relation to normal body volume and lower serum brain natriuretic peptide on admission.