Rusin G, Konieczyńska M, Bijak P, et al. - Given that oral anticoagulation (OAC) can increase the risk of bleeding, researchers investigated the impact of clinical factors and the level of atrial fibrillation (AF) knowledge on bleeding acceptance in patients with AF. Participants included 173 consecutive anticoagulated outpatients with AF (aged 68.7 ± 10.7 years; 39.3% male). Bleeding Ratio was evaluated based on the declared maximum number of major bleeds participants were willing to endure to avoid one stroke. The investigators used the Jessa AF Knowledge Questionnaire to evaluate knowledge of AF. Older people, with longer duration of AF, who suffered more commonly from heart failure, and were free of cerebrovascular events were found to have a lower Bleeding Ratio (0-3 accepted bleedings; n = 85; 49.1%) compared with those who had a higher Bleeding Ratio (≥ 4 accepted bleedings; n = 88; 50.9%). Age, prior thromboembolic and bleeding episodes were identified as the key determinants of the Bleeding Ratio among anticoagulated AF patients. There was no impact of the level of knowledge of AF on the Bleeding Ratio.