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Birthweight features of the infants of mothers diagnosed with diabetes at different gestational ages in south China from 2014 to 2018: A retrospective study

BMJ Open Apr 15, 2021

Huang XX, Jiang XM, Zheng QX, et al. - Researchers aimed at determining the birth weight of infants of mothers with gestational diabetes (IMGDs) at different gestational ages in order to generate new reference charts and curves for them. Further, they performed comparison of these with those of 159,334 infants in China to present more precise reference charts for the diagnosis of suspected abnormal birth weight of IMGDs. In addition, the key periods for such mothers were evaluated to control their weight in line with the difference of fetal weight of each two neighboring gestational ages. They analyzed data of 14,311 singleton live births at the gestational weeks 25–42. Among these, 7.26%, 87.04%, and 5.70% were recorded to have low birth weight, normal birth weight and macrosomia, respectively, and 5.69%, 84.42% and 9.89% were small for gestational age, appropriate for gestational age and large for gestational age, respectively. In the macrosomia group, reduction in the mean of all birth weight was noted for the first time in 2017 since 2014. Both the means of birth weight of male infants at gestational weeks 36–41 and of female at weeks 38–40 were greater when compared with that of the 159,334 infants. Relative to the former, there was > 10% increase of each weekly mean of IMGDs at gestational weeks 27–31 and 33–35. In accordance to this, they formulated new reference charts of birth weight for IMGDs in terms of different gestational age and gender. Based on findings, they suggest a possible utility of these charts as reference for more precise diagnosis and quick management of abnormal birth weight. The recognition of key periods for fetal weight gain was here suggested valuable for managing the weight of women with gestational diabetes.

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