Bansal N, et al. - In this observational study, researchers investigated if bioelectrical impedance analysis (BIA) measures of cell integrity (phase angle) and hydration (vector length) were associated with clinical outcomes in patients with chronic kidney disease (CKD) in the prospective multicenter Chronic Renal Insufficiency Cohort (CRIC) who had baseline single-frequency BIA performed. They used Cox proportional hazard models to examine the associations of phase angle and vector length with risks for mortality and progression of CKD and, used Fine and Gray models to determine the link with heart failure and atherosclerotic cardiovascular disease. A significant association of BIA-derived measures of cellular integrity and tissue hydration with death and incident heart failure, respectively, was found after adjusting for key confounders.